How it worksīoth versions of metoprolol belong to a class of drugs called beta-blockers. That means you may have to take it with hydrochlorothiazide or chlorthalidone. Metoprolol may be used as part of a combination therapy. However, metoprolol tartrate is also used to treat and prevent heart attacks, while metoprolol succinate is also used to treat heart failure. Why it’s usedīoth forms of metoprolol - metoprolol tartrate (Lopressor) and metoprolol succinate (Toprol-XL) - are used to: Metoprolol tartrate is an immediate-release version of metoprolol. Metoprolol succinate is an extended-release version of metoprolol, so it remains in your bloodstream for a longer time. The different salt forms enable the drugs to be used to treat different conditions. Lopressor is metoprolol tartrate, while Toprol-XL is metoprolol succinate. They’re both metoprolol, but they contain different salt forms. The two brand-name forms of metoprolol (as well as the different generic forms) are different versions of the medication. In some cases, they may not be available in all strengths or forms as the brand-name drugs. Generic drugs usually cost less than the brand-name versions. Metoprolol oral tablets are available as the brand-name drugs Lopressor and Toprol XL. It also comes in an injectable form that’s only given by a healthcare provider. It comes as immediate-release and extended-release oral tablets, and extended-release oral capsules.